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The RESET Myositis clinical trial is actively enrolling children and adults with myositis ages 6–75. Enrollment is currently underway at 35 sites across the United States and United Kingdom. All participants in this Phase 1/2 study receive CAR-T therapy, with no placebo group.

 

The study is evaluating an investigational CAR-T cell therapy approach that uses a patient’s own immune cells to target and reset parts of the immune system believed to be driving disease activity in juvenile myositis.

 

If you are interested in learning more, we encourage you to contact your physician through your patient portal or reach out directly to the participating site closest to you. The study team can help explain the screening and enrollment process, including whether travel or hotel support may be available if participation requires travel.

 

Questions? Please contact clinicaltrials@cabalettabio.com

Accepting Juvenile Patients:

  • Pediatric sites typically accept patients age 6 through age 26-28.
  • Patients over the age of 18 are encouraged to contact both the juvenile and adult site nearest them for additional eligibility information.


San Francisco, CA. UCSF. Contact: Zilan Zheng, 415-353-1301, Zilan.Zheng@ucsf.edu


Aurora, CO. Children’s Hospital Colorado. Contact: Dr. Kentaro Yomogida, Kentaro.Yomogida@childrenscolorado.org


St. Petersburg, FL. Johns Hopkins All Children’s Hospital. Contact: Jhanvi Patel, 727-767-2946, Jpatel77@jh.edu


Atlanta, GA. Children’s Healthcare of Atlanta. Contact: Judson Russell, 404-785-7263, Judson.russell@choa.org


Chicago, IL. Ann & Robert H. Lurie Children’s Hospital of Chicago. Contact: Tyler Sorensen, 312-277-6828, tsorensen@luriechildrens.org


Chicago, IL. University of Chicago Medical Center. Contact: Dr. Cuoghi Edends, cedens@bsd.uchicago.edu


Boston, MA. Boston Children’s Hospital. Contact: Kyle McBrearty, 617-355-2780, kyle.mcbrearty@childrens.harvard.edu


Ann Arbor, MI. University of Michigan. Contact: Abigail Whalen, 734-615-4466, abigaiwh@med.umich.edu


New York, NY. Hospital for Special Surgery. Contact: Janvi Bhatia, 212-774-2123, bhatiaj@hss.edu


New York, NY. Memorial Sloan Kettering. Contact: Atifah Osrat, 646-608-2091, osrata1@mskcc.org


Bronx, NY. Children’s Hospital at Montefiore. Contact: Emily Gillies, 718-696-2402, egillies@montefiore.org


Durham, NC. Duke University Medical Center. Contact: Lynn Rodgers, 919-668-2953, Lynn.rodgers@duke.edu


Philadelphia, PA. Children’s Hospital of Philadelphia. Contact: CARTintake@chop.edu


Dallas, TX. UT Southwestern Medical Center. Contact: Dr. Samuel John, dtpteam@childrens.com


Seattle, WA. Seattle Children’s Research Institute. Contact: Dr. Susan Shenoi, 206-987-2193, susan.shenoi@SeattleChildrens.org

Accepting Adult Patients:


Irvine, CA. University of California Irvine. Contact: Alpha Clinic, 949-824-3990, alphaclinic@uci.edu


Jacksonville, FL. Mayo Clinic Florida. Contact: Wesley Dillinger, 904-953-3626, dillinger.wesley@mayo.edu


Atlanta, GA. Emory University. Contact: Trinh Van, 404-712-3940, trinh.van@emory.edu


Chicago, IL. Northwestern Memorial Hospital. Contact: Kaitlin King, 312-695-0990, autoimmunesct@nm.org


Chicago, IL. University of Chicago Medical Center. Contact: Dr. Iazsmin Ventura, 773-702-6619, iventura@uchicago.edu


Kansas City, KS. University of Kansas Medical Center. Contact: Samantha Colgan, 913-945-9938, scolgan@kumc.edu


Rochester, MN. Mayo Clinic. Contact: Bridget Neja, 507-266-9150, neja.bridget@mayo.edu


New York, NY. Hospital for Special Surgery. Contact: Janvi Bhatia, 212-774-2123, bhatiaj@hss.edu


New York, NY. Memorial Sloan Kettering. Contact: Atifah Osrat, 646-608-2091, osrata1@mskcc.org


Chapel Hill, NC. University of North Carolina at Chapel Hill. Contact: Jennifer Poole, jennifer_poole@med.unc.edu


Portland, OR. Oregon Health & Science University. Contact: Katie Lewis, 503-908-9724, lewiskat@ohsu.edu


Pittsburgh, PA. UPMC Arthritis and Autoimmunity Center. Contact: Laurie Hope, hopelk@upmc.edu


Nashville, TN. Vanderbilt University Medical Center. Contact: Nur Ali, 615-875-5106, nur.ali@vumc.org


Houston, TX. Houston Methodist Hospital. Contact: Amelia A. Nounes, 346-356-3639, aanounes@houstonmethodist.org


Houston, TX. University of Texas MD Anderson Cancer Center. Contact: Christina Amos Briggs, 713-563-5076, aanounes@houstonmethodist.org

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